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Diskusikan dengan dokter perihal penggunaan diazepam pada orang lanjut usia atau anak-anak, karena risiko terjadinya efek samping bisa meningkat jika obat ini digunakan pada kelompok usia tersebut.
Benzodiazepine therapy is suggested being discontinued as soon as possible by a slow and gradual dose reduction regimen.[20][78] Tolerance develops towards the therapeutic consequences of benzodiazepines; one example is, tolerance occurs towards the anticonvulsant results and Because of this benzodiazepines are certainly not usually proposed with the long-phrase administration of epilepsy. Dose improves could get over the results of tolerance, but tolerance could then build to the upper dose and adverse effects may well boost.
Retain VALTOCO in a safe area to avoid misuse and abuse. Providing or gifting away VALTOCO may perhaps hurt Many others and is versus the legislation. Notify your Health care company if you have abused or been dependent on Alcoholic beverages, prescription medication, or Road medicine. It is far from regarded if VALTOCO is Protected and efficient in small children less than six several years of age. Critical SAFETY INFORMATION
ジアゼパムは、パーキンソン病の治療におけるレボドパの作用を阻害することがある。
Each VALTOCO only sprays 1 time and cannot be reused. Don't test or prime the nasal spray just before use.
Due to these active metabolites, the serum values of diazepam by yourself are not helpful in predicting the results of your drug. Diazepam contains a biphasic 50 percent-lifetime of about one particular to three times and two to 7 days with the Energetic metabolite desmethyldiazepam.[twenty] Almost all of the drug is metabolized; very little diazepam is excreted unchanged.[29] The elimination fifty percent-lifetime of diazepam and in addition the active metabolite desmethyldiazepam improves appreciably within the aged, which may bring about extended action, and also accumulation from the drug through repeated administration.[114]
Sufferers at a heightened danger of withdrawal adverse reactions following benzodiazepine discontinuation or immediate dosage reduction incorporate those that get larger dosages, and those who have experienced lengthier durations of use.
On account of varied responses to CNS-acting prescription drugs, initiate therapy with cheapest dose and boost as required. Not for use in pediatric clients under 6 months
Diazepam is contraindicated in people which has a recognized hypersensitivity to this drug and, as a consequence of not enough sufficient clinical knowledge, in pediatric clients underneath 6 months of age. Diazepam can also be contraindicated in clients with myasthenia gravis, intense respiratory insufficiency, critical hepatic insufficiency, and snooze apnea syndrome.
Diazepam is not suitable for everyone. Sure muscular conditions or respiratory ailments might be produced even worse by utilizing the drug; this read more also considerations psychological well being Conditions like depression or psychosis.
Contact a healthcare supplier right away if you have any new or worsening suicidal thoughts or relevant symptoms, Specially strange variations in temper, behaviors, views or thoughts.
中島らもの自伝的作品「今夜、すべてのバーで」にはアルコール依存症で入院した主人公が不眠症になり、医者にジアゼパムの注射を要求する場面がある。
Diazepam also can boost the depressive outcomes of Liquor and other types of sedatives. This is certainly why it shouldn't be utilized together with opioid medication unless no other cure is offered. [10]